| Spakeman | Spokesperson, a person who speaks on behalf of others |
| Spense | Guardian, a person who protects and watches over |
| Sperling | Sparrow, a person who is small and quick |
| Sprota | Young warrior, a person who is strong and courageous |
| Sprow | To sprout, a person who grows and develops quickly |
| Spyrling | Derived from Old English, possibly meaning 'spring' or 'source of water' |
| Staffy | Ford by a Landing Place |
| Stallone | A stallion or wild horse. |
| Stanclyf | Dweller by the stony cliff |
| Standcliff | Cliff or rocky outcropping near a standing or fixed point |
| Stansfield | One from the stony field |
| Stantway | Possibly derived from Old English, meaning 'standing place' or 'enclosure' |
| Starlyn | A bird like a small star |
| Steferd | Old English name, possibly meaning 'steep hill' or 'ford' |
| Stehen | Old English name, possibly meaning 'standing' or 'firm' |
| Stenin | Possibly derived from Old English, meaning 'stone' or 'rock' |
| Steuen | Old English name, possibly meaning 'steward' or 'servant' |
| Stewaro | Possibly derived from Old English, meaning 'steward' or 'servant' |
| Stilman | A quiet or peaceful man |
| Stirlingl | Derived from Old English, possibly meaning 'settlement by the stream' |
| Stofn | Old Norse name, meaning 'strong' or 'powerful' |
| Stony | Resembling a hard stone |
| Story | Derived from Old English, meaning 'narrative' or 'tale' |
| Stremu | Possibly derived from Old English, meaning 'stream' or 'brook' |
| Strongric | Derived from Old English, meaning 'strong ruler' or 'powerful leader' |
| Stubba | Old Norse name, meaning 'stump' or 'tree stump' |
| Stut | Old English name, possibly meaning 'stout' or 'strong' |
| Stybba | Old Norse name, meaning 'stump' or 'tree stump' |
| Styfic | Possibly derived from Old English, meaning 'stiff' or 'sturdy' |
| Style | A distinctive manner or way |
| Suan | A name meaning graceful jade |
| Sucga | Possibly derived from Old English, meaning 'suck' or 'suckling' |
| Sutclyf | Dweller by the south cliff |
| Swale | A low or marshy tract of land |
| Swatreband | Derived from Old English, possibly meaning 'swart' or 'dark band' |
| Swayne | A young man or an attendant |
| Sweppi | Old Norse name, meaning 'sweeper' or 'one who sweeps' |
| Sweting | Possibly derived from 'sweet' or 'swete', a term of endearment. |
| Sweyn | Young Man or Warrior |
| Swidhelm | Old English name meaning 'battle shield' or 'warrior's protection'. |